Reaction: ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region
- in pathway: Heme degradation
Bilirubin glucuronides (BMG and BDG) are transported out of hepatocytes through their apical surfaces into the bile ducts, mainly by ABCC2 (MRP2) but also by the tetrameric efflux pump ATP-binding cassette sub-family G member 2 (ABCG2) (Xu et al. 2004).
Reaction - small molecule participants:
Pi [cytosol]
ADP [cytosol]
H2O [cytosol]
ATP [cytosol]
Reactome.org reaction link: R-HSA-9661417
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Reaction input - small molecules:
water
ATP(4-)
Reaction output - small molecules:
hydrogenphosphate
ADP(3-)
Reactome.org link: R-HSA-9661417