Reaction: BIL binds ALB
- in pathway: Heme degradation
The serum protein albumin (ALB) binds unconjugated bilirubin (BIL), preventing BIL toxicity (Griffiths et al. 1975, Weisiger et al. 2001). ALB-bound BIL is a water-soluble complex and is transported to the liver where it is selectively absorbed by hepatocytes.
Reaction - small molecule participants:
BIL [extracellular region]
BIL [extracellular region]
Reactome.org reaction link: R-HSA-9661432
======
Reaction input - small molecules:
bilirubin(2-)
bilirubin(2-)
Reaction output - small molecules:
Reactome.org link: R-HSA-9661432