Reaction: ADAM17 binds Zn2+
- in pathway: CD163 mediating an anti-inflammatory response
A crystallography study revealed that disintegrin and metalloproteinase domain-containing protein 17 (ADAM17) requires Zinc as a cofactor to function properly (Maskos et al. 1998).
Reaction - small molecule participants:
Zn2+ [Golgi membrane]
Reactome.org reaction link: R-HSA-9662773
======
Reaction input - small molecules:
zinc(2+)
Reaction output - small molecules:
Reactome.org link: R-HSA-9662773