Reaction: ATP2B1 (PMCA1) transports Ca2+ from the cytosol to the extracellular region
ATP2B1 (PMCA1) located in the basolateral membrane of inner hair cells transports calcium ions from the cytosol to the extracellular region with concomitant hydrolysis of ATP (inferred from the rat homolog). The efflux of calcium ions is believed to participate in repolarization of the cell.
Reaction - small molecule participants:
Pi [cytosol]
ADP [cytosol]
Ca2+ [extracellular region]
ATP [cytosol]
Ca2+ [cytosol]
Reactome.org reaction link: R-HSA-9664214
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Reaction input - small molecules:
ATP(4-)
calcium(2+)
Reaction output - small molecules:
hydrogenphosphate
ADP(3-)
calcium(2+)
Reactome.org link: R-HSA-9664214