Reaction: PM20D1 hydrolyzes oleoyl-phe
- in pathway: Oleoyl-phe metabolism
Extracellular PM20D1 (N-fatty-acyl-amino acid synthase/hydrolase PM20D1) catalyzes the reversible hydrolysis of oleoyl-phe (N-(9Z-octadecenoyl)-L-phenylalanine) to form L-phenylalanine (L-phe) and oleate ((9Z)-octadecenoate). In addition to the hydrolysis of oleoyl-phe (N-(9Z-octadecenoyl)-L-phenylalanine) annotated here, purified PM20D1 can hydrolyze a variety of n-acyl amino acids (Long et al. 2016).
Reaction - small molecule participants:
L-Phe [extracellular region]
oleate [extracellular region]
H2O [extracellular region]
oleoyl-Phe [extracellular region]
Reactome.org reaction link: R-HSA-9673054
======
Reaction input - small molecules:
water
N-oleoyl-L-phenylalaninate
Reaction output - small molecules:
L-phenylalanine zwitterion
oleate
Reactome.org link: R-HSA-9673054