Reaction: USP30 deubiquitinates ATM dimer:Ub-p-PEX5
- in pathway: Pexophagy
The deubiquitinase, Ubiquitin carboxyl-terminal hydrolase 30 (USP30) counters the action of E3 ligase on peroxisomal membrane proteins. USP30 can remove ubiquitin moieties from PEX5 thereby preventing pexophagy (Riccio V et al. 2019, Marcassa E et al. 2019)
Reaction - small molecule participants:
H2O [cytosol]
Reactome.org reaction link: R-HSA-9674127
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Reaction input - small molecules:
water
Reaction output - small molecules:
Reactome.org link: R-HSA-9674127