Reaction: Spike trimer glycoside chains are extended
- in pathway: Maturation of spike protein
In the cis- to medial Golgis, conversion of high-mannose to complex type N-glycans side chains of Spike occurs. The N-acetylglucosaminyltransferase called GlcNAc-TI (MGAT1) adds a GlcNAc residue in the core of some high-mannose chains (Ritchie et al, 2010; Nal et al, 2005, Song et al, 2004).
Reaction - small molecule participants:
UDP [endoplasmic reticulum-Golgi intermediate compartment]
H+ [endoplasmic reticulum-Golgi intermediate compartment]
UDP-N-acetyl-alpha-D-glucosamine(2−) [endoplasmic reticulum-Golgi intermediate compartment]
Reactome.org reaction link: R-HSA-9683648
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Reaction input - small molecules:
UDP-N-acetyl-alpha-D-glucosamine(2-)
Reaction output - small molecules:
UDP
hydron
Reactome.org link: R-HSA-9683648