Reaction: Polyadenylation of SARS-CoV-1 genomic RNA (plus strand)
- in pathway: Replication of the SARS-CoV-1 genome
SARS-CoV-1 plus strand genomic RNA, like genomic RNAs of other coronaviruses, possesses a polyadenylation signal in its 3'UTR and is polyadenylated by an undetermined viral RNA polymerase, possibly nsp8 or nsp12 (Spagnolo and Hogue 2000, Peng et al. 2016, Tvarogova et al. 2019).
Reaction - small molecule participants:
PPi [cytosol]
ATP [cytosol]
Reactome.org reaction link: R-HSA-9685519
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Reaction input - small molecules:
ATP(4-)
Reaction output - small molecules:
diphosphate(3-)
Reactome.org link: R-HSA-9685519