Reaction: HRH3 binds Hist
- in pathway: Histamine receptors
Histamine H3 receptor (HRH3) (Lovenberg et al. 1999) is predominantly expressed in the CNS and is involved in decreasing the release of neurotransmitters such as histamine, acetylcholine, norepinephrine and serotonin. There are currently at least six isoforms of the H3 receptor in humans of which isoforms 1,2 and 4 encode functional proteins (Wellendorph et al. 2002).
Reaction - small molecule participants:
Hist [extracellular region]
Reactome.org reaction link: R-HSA-9692880
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Reaction input - small molecules:
histaminium
Reaction output - small molecules:
Reactome.org link: R-HSA-9692880