Reaction: O-glycosylation of 3a is terminated
- in pathway: Maturation of protein 3a
This COVID-19 event has been created by a combination of computational inference (see https://reactome.org/documentation/inferred-events) from SARS-CoV-1 data and manual curation, as described in the summation for the overall SARS-CoV-2 infection pathway.
A sialyltransferase adds a terminal sialic acid moiety to protein 3a with an O-linked glycosyl side chain. This glycosylated form later is associated with the virion (Oostra et al, 2006)
A sialyltransferase adds a terminal sialic acid moiety to protein 3a with an O-linked glycosyl side chain. This glycosylated form later is associated with the virion (Oostra et al, 2006)
Reaction - small molecule participants:
CMP [endoplasmic reticulum-Golgi intermediate compartment]
CMP-Neu5Ac [endoplasmic reticulum-Golgi intermediate compartment]
Reactome.org reaction link: R-HSA-9694718
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Reaction input - small molecules:
CMP-N-acetyl-beta-neuraminate(2-)
Reaction output - small molecules:
cytidine 5'-monophosphate
Reactome.org link: R-HSA-9694718