Reaction: KCNJ2 (KIR2.1) transports K+ from the extracellular region to the cytosol
- in pathway: Sensory perception of sour taste
The KCNJ2 inward rectifying potassium channel preferentially transports K+ ions from the extracellular region to the cytosol (inferred from the mouse homolog). In type III taste cells, the increase in cytosolic H+ caused by acidic compounds inhibits the activity of KCNJ2 (inferred from mouse homologs in Ye et al. 2016).
Reaction - small molecule participants:
K+ [cytosol]
K+ [extracellular region]
Reactome.org reaction link: R-HSA-9729870
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Reaction input - small molecules:
potassium(1+)
Reaction output - small molecules:
potassium(1+)
Reactome.org link: R-HSA-9729870