Reaction: ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA
- in pathway: Aspirin ADME
ACSM2B-like enzymes catalyze the transfer of acyl groups onto CoA (Vessey et al, 1976). This is a necessary step for conjugation of 2,5-DHBA with glycine (Wilson et al., 1978).
Reaction - small molecule participants:
AMP [mitochondrial matrix]
PPi [mitochondrial matrix]
2,5-DHB-CoA [mitochondrial matrix]
CoA-SH [mitochondrial matrix]
2,5-DHBA [mitochondrial matrix]
ATP [mitochondrial matrix]
Reactome.org reaction link: R-HSA-9749971
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Reaction input - small molecules:
coenzyme A(4-)
2,5-dihydroxybenzoate
ATP(4-)
Reaction output - small molecules:
adenosine 5'-monophosphate(2-)
diphosphate(3-)
2,5-dihydroxybenzoyl-CoA
Reactome.org link: R-HSA-9749971