Reaction: ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells
- in pathway: Aspirin ADME
ATP-binding cassette sub-family C members 2 and 3 (ABCC2, ABCC3) transport glucuronides out of liver and kidney cells. They also are able to transport organic anions and amino acid conjugates (Cui et al, 1999; Zelcer et al, 2001; Järvinen, 2019).
Reaction - small molecule participants:
Pi [cytosol]
ADP [cytosol]
H2O [cytosol]
ATP [cytosol]
Reactome.org reaction link: R-HSA-9750656
======
Reaction input - small molecules:
water
ATP(4-)
Reaction output - small molecules:
hydrogenphosphate
ADP(3-)
Reactome.org link: R-HSA-9750656