Reaction: NME1,2 hexamers phosphorylate RBV-DP
- in pathway: Ribavirin ADME
Both nucleoside diphosphate kinases A and B (NME1, NME2) hexamers phosphorylate ribavirin diphosphate (RBV-DP) to the triphosphate (RBV-TP) (Bourdais et al, 1996; Gallois-Montbrun et al, 2003).
Reaction - small molecule participants:
ADP [cytosol]
RBV-TP [cytosol]
RBV-DP [cytosol]
ATP [cytosol]
Reactome.org reaction link: R-HSA-9755013
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Reaction input - small molecules:
ribavirin 5'-diphosphate(3-)
ATP(4-)
Reaction output - small molecules:
ADP(3-)
ribavirin 5'-triphosphate(4-)
Reactome.org link: R-HSA-9755013