Reaction: atROL binds to RBP2
- in pathway: Retinoid metabolism and transport
In enterocytes, the dominant retinol-binding protein is RBP2 (CRBPII) which is abundant and binds retinol faster than the cell membrane. So, even though lipophilic retinol can easily enter the cell membrane of bowel enterocytes, it is collected by the abundancy of RBP2 into the enterocyte cytosol where it is further processed (Inagami & Ong 1997).
Reaction - small molecule participants:
atROL [plasma membrane]
Reactome.org reaction link: R-HSA-975633
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Reaction input - small molecules:
all-trans-retinol
Reaction output - small molecules:
Reactome.org link: R-HSA-975633