Reaction: BCMO1:Fe2+ cleaves betaC to atRAL
- in pathway: Retinoid metabolism and transport
As long as vitamin A is needed, beta-carotene-monooxygenase (BCMO1) catalyses the cleavage of carotenes, resulting mainly in retinal (Fierce et al. 2008).
Reaction - small molecule participants:
atRAL [cytosol]
O2 [cytosol]
betaC [plasma membrane]
Reactome.org reaction link: R-HSA-975635
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Reaction input - small molecules:
dioxygen
beta-carotene
Reaction output - small molecules:
all-trans-retinal
Reactome.org link: R-HSA-975635