Reaction: Serum amyloid P-component forms homopentamers
- in pathway: Amyloid fiber formation
Serum amyloid P component (SAP) is a member of the pentraxin family, characterized by the formation of pentameric ring structures. Each member of the ring has two associated calcium ions. SAP is an acute phase reactant, highly induced by IL-6. It has 50% homology with the related C-reactive peptide.
Reaction - small molecule participants:
Ca2+ [extracellular region]
Reactome.org reaction link: R-HSA-976723
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Reaction input - small molecules:
calcium(2+)
Reaction output - small molecules:
Reactome.org link: R-HSA-976723