Reaction: Cipro:ALB dissociates
- in pathway: Ciprofloxacin ADME
Distribution and free concentration of various drugs can be significantly altered as a result of their binding to serum albumin (ALB). Cipro binds to ALB in a pH dependent manner. Slight pH variations in different extracellular environments may affect the dissociation of the Cipro:ALB complex (Ahmad et al, 2006; Anand et al, 2012; Varshney et al, 2014).
Reaction - small molecule participants:
Cipro [extracellular region]
Reactome.org reaction link: R-HSA-9794475
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Reaction input - small molecules:
Reaction output - small molecules:
ciprofloxacin zwitterion
Reactome.org link: R-HSA-9794475