Reaction: ST3GAL1-4 transfers sialic acid to the T antigen at the alpha 3 position
- in pathway: Termination of O-glycan biosynthesis
The human genes ST3GAL1-4 encode for sialyltransferases1-4 respectively (Shang et al. 1999, Kim et al. 1996, Kitagawa & Paulson 1993, Basu et al. 1993). They add silaic acid (Neu5Ac) onto the T antigen forming an alpha-3-sialyl O-glycan.
Reaction - small molecule participants:
CMP [Golgi lumen]
CMP-Neu5Ac [Golgi lumen]
Reactome.org reaction link: R-HSA-981497
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Reaction input - small molecules:
CMP-N-acetyl-beta-neuraminate(2-)
Reaction output - small molecules:
cytidine 5'-monophosphate(2-)
Reactome.org link: R-HSA-981497