Reaction: SRPK1 phosphorylates PRM1 in PRM1:dsDNA
In the male pronucleus of the zygote, Serine-arginine-rich protein-specific kinase 1 (SRPK1) phosphorylates protamine 1 (PRM1) on serine-9. This reaction is inferred from mouse homologs in which Srpk1 phosphorylates Prm1 on both serine-9 and serine-43. Human PRM1, however, does not have a serine residue that corresponds to serine-43 of mouse Prm1.
Reaction - small molecule participants:
ADP [nucleoplasm]
ATP [nucleoplasm]
Reactome.org reaction link: R-HSA-9821982
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Reaction input - small molecules:
ATP(4-)
Reaction output - small molecules:
ADP(3-)
Reactome.org link: R-HSA-9821982