Reaction: DIS3L2 hydrolyzes uridylated mRNA
PABPN1 bound to 3' uridylated mRNA recruits DIS3L2, an exosome-independent 3'-5' exoribonuclease that degrades the mRNA (inferred from mouse homologs).
Reaction - small molecule participants:
H2O [cytosol]
Reactome.org reaction link: R-HSA-9822437
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Reaction input - small molecules:
water
Reaction output - small molecules:
Reactome.org link: R-HSA-9822437