Reaction: p-PKR dimer phosphorylates PTPN2
- in pathway: PKR-mediated signaling
Protein kinase R (PKR, EIF2AK2) phosphorylates the tyrosine-protein phosphatase PTPN2 (TCPTP) on an unknown residue. It is unclear if this directly affects the catalytic activity of PTPN2 (Wang et al, 2006).
Reaction - small molecule participants:
ADP [cytosol]
ATP [cytosol]
Reactome.org reaction link: R-HSA-9836515
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Reaction input - small molecules:
ATP(4-)
Reaction output - small molecules:
ADP(3-)
Reactome.org link: R-HSA-9836515