Reaction: SYK autophosphorylates at the activated BCR

- in pathway: Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
SHP1 regulates BCR signaling by dephosphorylating CD79A/CD79B (IGA/IGB) and its downstream signaling molecules SYK and SLP65 promoting Ca2+ efflux from the cell9 (Adachi et al. 2001, Chen et al. 2004).
Reaction - small molecule participants:
ADP [cytosol]
ATP [cytosol]
ADP [cytosol]
ATP [cytosol]
Reactome.org reaction link: R-HSA-983707

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Reaction input - small molecules:
ATP(4-)
ChEBI:30616
ATP(4-)
ChEBI:30616
Reaction output - small molecules:
ADP(3-)
ChEBI:456216
ADP(3-)
ChEBI:456216
Reactome.org link: R-HSA-983707