Reaction: SLC25A42 exchanges cytosolic CoA-SH for mitochondrial matrix ADP
- in pathway: Vitamin B5 (pantothenate) metabolism
SLC25A42 associated with the inner mitochondrial membrane mediates the exchange of cytosolic CoA-SH for mitochondrial ADP. In vitro, SLC25A42 also shows a high transport affinity for dephospho-CoA (DP-CoA), and adenosine 3′,5′-diphosphate (PAP), not annotated here (Cavestro et al. 2023, Fiermonte et al. 2009).
Reaction - small molecule participants:
CoA-SH [mitochondrial matrix]
ADP [cytosol]
ADP [mitochondrial matrix]
CoA-SH [cytosol]
Reactome.org reaction link: R-HSA-9837333
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Reaction input - small molecules:
ADP(3-)
coenzyme A(4-)
Reaction output - small molecules:
coenzyme A(4-)
ADP(3-)
Reactome.org link: R-HSA-9837333