Molecule: 7alpha-hydroxycholest-4-en-3-one

A cholestanoid consisting of a cholesterol core having an oxo group at the 3-position, a C=C bond at the 4,5-position and an alpha-hydroxy group at the 7-position.
Synonyms for 7alpha-hydroxycholest-4-en-3-one :
7alpha-Hydroxy-4-cholesten-3-one
7alpha-Hydroxycholest-4-en-3-one
7alpha-hydroxycholest-4-en-3-one
Cholest-4-en-7alpha-ol-3-one
Molecular Formula: C27H44O2
Molecular wt: 400.63706 g/mole
Charge: 0
SMILES: [H][C@@]1(CC[C@@]2([H])[C@]3([H])[C@H](O)CC4=CC(=O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)CCCC(C)C
InChIKey: IOIZWEJGGCZDOL-RQDYSCIWSA-N
InChI=1S/C27H44O2/c1-17(2)7-6-8-18(3)21-9-10-22-25-23(12-14-27(21,22)5)26(4)13-11-20(28)15-19(26)16-24(25)29/h15,17-18,21-25,29H,6-14,16H2,1-5H3/t18-,21-,22+,23+,24-,25+,26+,27-/m1/s1
CHEBI:17899
Sample reactions for this molecule:
4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one
7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one
CYP8B1 12-hydroxylates 4CHOL7aOLONE
CYP8B1 12-hydroxylates 4CHOL7aOLONE