Pathway: ERK/MAPK targets
Reactions in pathway: ERK/MAPK targets :
ERK/MAPK targets
ERK/MAPK kinases have a number of targets within the nucleus, usually transcription factors or other kinases. The best known targets, ELK1, ETS1, ATF2, MITF, MAPKAPK2, MSK1, RSK1/2/3 and MEF2 are annotated here.
Innate immunity encompases the nonspecific part of immunity tha are part of an individual's natural biologic makeup
Humans are exposed to millions of potential pathogens daily, through contact, ingestion, and inhalation. Our ability to avoid infection depends on the adaptive immune system and during the first critical hours and days of exposure to a new pathogen, our innate immune system.