Reaction: PE is methylated to PC by PEMT
- in pathway: Synthesis of PC
At the endoplasmic reticulum (ER) membrane, phosphatidylethanolamine N-methyltransferase (PEMT) methylates phosphatidylethanolamine (PE) and produces phosphatidylcholine (PC) (Vance & Ridgway 1998, Shields et al. 2001, Guan et al. 1999).
Reaction - small molecule participants:
PC [endoplasmic reticulum membrane]
AdoHcy [cytosol]
AdoMet [cytosol]
PE [endoplasmic reticulum membrane]
Reactome.org reaction link: R-HSA-1483174
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Reaction input - small molecules:
S-adenosyl-L-methionine zwitterion
phosphatidylethanolamine zwitterion
Reaction output - small molecules:
1,2-diacyl-sn-glycero-3-phosphocholine
S-adenosyl-L-homocysteine zwitterion
Reactome.org link: R-HSA-1483174