Reaction: Ascorbate can reduce the BH3 radical back to BH4
Ascorbate (AscH-) can reduce the BH3 radical back to BH4, thereby maintaining BH4 levels (Baker et al. 2001, Patel et al. 2002, Kuzkaya et al. 2003).
Reaction - small molecule participants:
BH4 [cytosol]
Asc.- [cytosol]
AscH- [cytosol]
BH3. [cytosol]
Reactome.org reaction link: R-HSA-1497855
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Reaction input - small molecules:
L-ascorbate
5,6,7,8-tetrahydrobiopterin radical cation
Reaction output - small molecules:
5,6,7,8-tetrahydrobiopterin
monodehydro-L-ascorbate(1-)
Reactome.org link: R-HSA-1497855