Molecule: 5,6,7,8-tetrahydrobiopterin

Synonyms for 5,6,7,8-tetrahydrobiopterin :
2-Amino-6-(1,2-dihydroxypropyl)-5,6,7,8-tetrahydoro-4(1H)-pteridinone
5,6,7,8-TETRAHYDROBIOPTERIN
5,6,7,8-Tetrahydrobiopterin
5,6,7,8-tetrahydrobiopterin
BH4
Tetrahydrobiopterin
Molecular Formula: C9H15N5O3
Molecular wt: 241.24730 g/mole
Charge: 0
SMILES: CC(O)C(O)C1CNc2nc(N)[nH]c(=O)c2N1
InChIKey: FNKQXYHWGSIFBK-UHFFFAOYSA-N
InChI=1S/C9H15N5O3/c1-3(15)6(16)4-2-11-7-5(12-4)8(17)14-9(10)13-7/h3-4,6,12,15-16H,2H2,1H3,(H4,10,11,13,14,17)
CHEBI:15372
Sample reactions for this molecule:
PTHP is reduced to BH4 by sepiapterin reductase (SPR)
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle
Salvage - BH2 is reduced to BH4 by DHFR
BH2 binding can lead to eNOS uncoupling
BH2 binding can lead to eNOS uncoupling
BH4 is oxidised to the BH3 radical during the eNOS catalytic cycle
Ascorbate can reduce the BH3 radical back to BH4
Peroxynitrite can oxidise BH4 to the BH3 radical