Reaction: I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol
- in pathway: Synthesis of IP3 and IP4 in the cytosol
Inositol-tetrakisphosphate 1-kinase (ITPK1) dephosphorylates inositol 1,3,4,6-tetrakisphosphate (I(1,3,4,6)P4) to inositol 3,4,6-trisphosphate (I(3,4,6)P3) (Ho et al. 2002).
Reaction - small molecule participants:
Pi [cytosol]
I(3,4,6)P3 [cytosol]
I(1,3,4,6)P4 [cytosol]
H2O [cytosol]
Reactome.org reaction link: R-HSA-1855159
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Reaction input - small molecules:
myo-inositol 1,3,4,6-tetrakisphosphate(8-)
water
Reaction output - small molecules:
hydrogenphosphate
1D-myo-inositol 3,4,6-trisphosphate
Reactome.org link: R-HSA-1855159