Molecule: myo-inositol 1,3,4,6-tetrakisphosphate(8-)

Octaanion of myo-inositol 1,3,4,6-tetrakisphosphate arising from global deprotonation of the phosphate OH groups; major species at pH 7.3.
Synonyms for myo-inositol 1,3,4,6-tetrakisphosphate(8-) :
1D-myo-inositol 1,3,4,6-tetrakisphosphate
myo-inositol 1,3,4,6-tetrakisphosphate octaanion
Molecular Formula: C6H8O18P4
Molecular wt: 492.01200 g/mole
Charge: -8
SMILES: O[C@H]1[C@H](OP([O-])([O-])=O)[C@@H](OP([O-])([O-])=O)[C@@H](O)[C@@H](OP([O-])([O-])=O)[C@@H]1OP([O-])([O-])=O
InChIKey: ZAWIXNGTTZTBKV-JMVOWJSSSA-F
InChI=1S/C6H16O18P4/c7-1-3(21-25(9,10)11)5(23-27(15,16)17)2(8)6(24-28(18,19)20)4(1)22-26(12,13)14/h1-8H,(H2,9,10,11)(H2,12,13,14)(H2,15,16,17)(H2,18,19,20)/p-8/t1-,2+,3-,4+,5-,6+
CHEBI:57660
Sample reactions for this molecule:
I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol
I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol
I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol
I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol
I(1,3,4,6)P4 transports from the cytosol to the nucleus
I(1,3,4,6)P4 transports from the cytosol to the nucleus
I(1,3,4,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus
ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4
MLKL binds IP4, IP5 and IP6