Meta-Biol : Reactions : ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4

Reaction: ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4

- in pathway: Factors involved in megakaryocyte development and platelet production

Inositol-tetrakisphosphate 1-kinase (ITPK1) phosphorylates Ins(1,3,4)P3 on O-6 to form Ins(1,3,4,6)P4, an essential molecule in the hexakisphosphate (InsP6) pathway.

Reaction - small molecule participants:

I(1,3,4,6)P4 [cytosol]

ADP [cytosol]

ATP [cytosol]

I(1,3,4)P3 [cytosol]

Reactome.org reaction link: R-HSA-2267372

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Reaction input - small molecules:

ATP(4-)

ChEBI:30616

1D-myo-inositol 1,3,4-trisphosphate(6-)

ChEBI:58414

Reaction output - small molecules:

myo-inositol 1,3,4,6-tetrakisphosphate(8-)

ChEBI:57660

ADP(3-)

ChEBI:456216

Reactome.org link: R-HSA-2267372