Reaction: HMBL spontaneously transforms to URO1
- in pathway: Heme biosynthesis
Hydroxymethybilane (HMBL) can spontaneously cyclize and rearrange to form uroporphyrinogen I (URO1).
Reaction - small molecule participants:
URO1 [cytosol]
H2O [cytosol]
HMBL [cytosol]
Reactome.org reaction link: R-HSA-190168
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Reaction input - small molecules:
preuroporphyrinogen(8-)
Reaction output - small molecules:
uroporphyrinogen I(8-)
water
Reactome.org link: R-HSA-190168