Reaction: Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate
- in pathway: Cholesterol biosynthesis
Cytosolic isopentenyl diphosphate isomerase (IPP isomerase) catalyzes an essential activation step in the isoprenoid biosynthetic pathway. It rearranges isopentenyl pyrophosphate into its highly electrophilic isomer, dimethylallyl pyrophosphate (DMAPP). IPP isomerase may also be located in human peroxisomes but it's function there is not clear.
Reaction - small molecule participants:
DMAPP [cytosol]
IPPP [cytosol]
Reactome.org reaction link: R-HSA-191382
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Reaction input - small molecules:
isopentenyl diphosphate
Reaction output - small molecules:
prenyl diphosphate
Reactome.org link: R-HSA-191382