Reaction: Mevalonate-5-phosphate is further phosphorylated.
- in pathway: Cholesterol biosynthesis
Phosphomevalonate kinase (PMK) catalyzes the reversible, ATP-dependent phosphorylation of mevalonate-5-phosphate, producing mevalonate-5-pyrophosphate.
Reaction - small molecule participants:
ADP [cytosol]
MVA5PP [cytosol]
ATP [cytosol]
MVA5P [cytosol]
Reactome.org reaction link: R-HSA-191422
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Reaction input - small molecules:
ATP(4-)
(R)-5-phosphonatomevalonate(3-)
Reaction output - small molecules:
ADP(3-)
(R)-5-diphosphomevalonic acid
Reactome.org link: R-HSA-191422