Reaction: Thiolysis of 3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA yields chenodeoxycholoyl-CoA (3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA
3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA and CoASH react to form chenodeoxycholoyl-CoA (3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA. This reaction, in the peroxisomal matrix, is catalyzed by peroxisomal thiolase 2 (sterol carrier protein 2).
Reaction - small molecule participants:
propionyl CoA [peroxisomal matrix]
chenodeoxycholoyl-CoA [peroxisomal matrix]
3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA [peroxisomal matrix]
CoA-SH [peroxisomal matrix]
Reactome.org reaction link: R-HSA-193533
======
Reaction input - small molecules:
3alpha,7alpha-dihydroxy-24-oxo-5beta-cholestan-26-oyl-CoA
coenzyme A(4-)
Reaction output - small molecules:
propionyl-CoA
chenodeoxycholoyl-CoA(4-)
Reactome.org link: R-HSA-193533