Molecule: propionyl-CoA

An acyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of propionic acid.
Synonyms for propionyl-CoA :
Propanoyl-CoA
Propionyl coenzyme A
Propionyl-CoA
Propionyl-coenzyme A
S-Propionyl-coenzym-A
S-Propionylcoenzyme A
S-propanoyl-CoA
S-propanoyl-coenzyme A
propanoyl-coenzyme A
Molecular Formula: C24H40N7O17P3S
Molecular wt: 823.600 g/mole
Charge: 0
SMILES: CCC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N
InChIKey: QAQREVBBADEHPA-IEXPHMLFSA-N
InChI=1S/C24H40N7O17P3S/c1-4-15(33)52-8-7-26-14(32)5-6-27-22(36)19(35)24(2,3)10-45-51(42,43)48-50(40,41)44-9-13-18(47-49(37,38)39)17(34)23(46-13)31-12-30-16-20(25)28-11-29-21(16)31/h11-13,17-19,23,34-35H,4-10H2,1-3H3,(H,26,32)(H,27,36)(H,40,41)(H,42,43)(H2,25,28,29)(H2,37,38,39)/t13-,17-,18-,19+,23-/m1/s1
CHEBI:15539
Propionyl-CoA
Sample reactions for this molecule:
Thiolysis of 3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA yields choloyl-CoA (3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA
Thiolysis of 3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA yields chenodeoxycholoyl-CoA (3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA
Formation of DHA-CoA catalysed by sterol carrier protein X (SCPx)
3-ketopristanoyl-CoA + CoASH => 4,8,12-trimethyltridecanoyl-CoA + propionyl-CoA
4,8,12-trimethyltridecanoyl-CoA + 2 O2 + 2 H2O + 2 NAD+ + 2 CoASH => 4,8-dimethylnonanoyl-CoA + 2 H2O2 + 2 NADH + 2 H+ + acetyl-CoA + propionyl-CoA
propionyl-CoA + carnitine => propionylcarnitine + CoASH
alpha-methyl-acetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA
methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+
propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate