Reaction: Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA
- in pathway: Linoleic acid (LA) metabolism
Docosatetraenoyl-CoA is elongated to tetracosatetraenoyl-CoA (TTA-CoA, 9,12,15,18-tetracosatetraenoic acid, 9,12,15,18-24:4(n-6)) by the elongase enzyme ELOVL2.
Reaction - small molecule participants:
TTA-CoA [endoplasmic reticulum lumen]
H2O [endoplasmic reticulum lumen]
CoA-SH [endoplasmic reticulum lumen]
CO2 [endoplasmic reticulum lumen]
Malonyl-CoA [endoplasmic reticulum lumen]
DTA-CoA [endoplasmic reticulum lumen]
NADPH [endoplasmic reticulum lumen]
Reactome.org reaction link: R-HSA-2046095
======
Reaction input - small molecules:
malonyl-CoA(5-)
(7Z,10Z,13Z,16Z)-docosatetraenoyl-CoA
NADPH
Reaction output - small molecules:
(9Z,12Z,15Z,18Z)-tetracosatetraenoyl-CoA
water
coenzyme A(4-)
carbon dioxide
Reactome.org link: R-HSA-2046095