Molecule: malonyl-CoA(5-)

Pentaanion of malonyl-CoA arising from deprotonation of phosphate, diphosphate and carboxylic acid functions.
Synonyms for malonyl-CoA(5-) :
malonyl-CoA
Molecular Formula: C24H33N7O19P3S
Molecular wt: 848.54100 g/mole
Charge: -5
SMILES: CC(C)(COP([O-])(=O)OP([O-])(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP([O-])([O-])=O)n1cnc2c(N)ncnc12)[C@@H](O)C(=O)NCCC(=O)NCCSC(=O)CC([O-])=O
InChIKey: LTYOQGRJFJAKNA-DVVLENMVSA-I
InChI=1S/C24H38N7O19P3S/c1-24(2,19(37)22(38)27-4-3-13(32)26-5-6-54-15(35)7-14(33)34)9-47-53(44,45)50-52(42,43)46-8-12-18(49-51(39,40)41)17(36)23(48-12)31-11-30-16-20(25)28-10-29-21(16)31/h10-12,17-19,23,36-37H,3-9H2,1-2H3,(H,26,32)(H,27,38)(H,33,34)(H,42,43)(H,44,45)(H2,25,28,29)(H2,39,40,41)/p-5/t12-,17-,18-,19+,23-/m1/s1
CHEBI:57384
Sample reactions for this molecule:
acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate
Elongation of arachidonyl-CoA to docosatetraenoyl-CoA
Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA
Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA
Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA
Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA
Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA
ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA
ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA
ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA