Reaction: H2Se is methylated to MeSeH by H2Se methyltransferase
- in pathway: Metabolism of ingested SeMet, Sec, MeSec into H2Se
A yet to be identified enzyme with hydrogen selenide methyltransferase (HSeMT) activity is involved in the methylation of hydrogen selenide (H2Se) into methylselenol aka methaneselenol (MeSeH) in tandem with S-adenosylmethionine (AdoMet) transforming into S-adenosylhomocysteine (AdoHcy). This reaction is inferred from the event in rat (Ohta and Suzuki 2008, Hsieh and Ganther 1977).
Reaction - small molecule participants:
AdoHcy [cytosol]
MeSeH [cytosol]
H2Se [cytosol]
AdoMet [cytosol]
Reactome.org reaction link: R-HSA-2408536
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Reaction input - small molecules:
selane
S-adenosyl-L-methionine zwitterion
Reaction output - small molecules:
S-adenosyl-L-homocysteine zwitterion
methylselenol
Reactome.org link: R-HSA-2408536