Reaction: MeSeH is methylated to Me2Se by MeSeH methyltransferase
- in pathway: Methylation of MeSeH for excretion
A yet to be identified enzyme with methylselenol methyltransferase (MeSeHMT) activity is involved in the methylation of methylselenol aka methaneselenol (MeSeH) into dimethyl selenide (Me2Se) in tandem with S-adenosylmethionine (AdoMet) transforming into S-adenosylhomocysteine (AdoHcy). This reaction is inferred from the event in rat (Ohta and Suzuki 2008, Hsieh and Ganther 1977).
Reaction - small molecule participants:
Me2Se [cytosol]
AdoHcy [cytosol]
AdoMet [cytosol]
MeSeH [cytosol]
Reactome.org reaction link: R-HSA-2408541
======
Reaction input - small molecules:
S-adenosyl-L-methionine zwitterion
methylselenol
Reaction output - small molecules:
dimethylselenide
S-adenosyl-L-homocysteine zwitterion
Reactome.org link: R-HSA-2408541