Reaction: Me2Se is methylated to Me3Se+ by INMT
- in pathway: Methylation of MeSeH for excretion
Indolethylamine N-methyltransferase (INMT) is involved in the methylation of dimethyl selenide (Me2Se) into trimethylselenonium (Me3Se+) in tandem with S-adenosylmethionine (AdoMet) transforming into S-adenosylhomocysteine (AdoHcy). This reaction is inferred from the event in mouse (Mozier et al. 1988).
Reaction - small molecule participants:
Me3Se+ [cytosol]
AdoHcy [cytosol]
Me2Se [cytosol]
AdoMet [cytosol]
Reactome.org reaction link: R-HSA-2408554
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Reaction input - small molecules:
dimethylselenide
S-adenosyl-L-methionine zwitterion
Reaction output - small molecules:
trimethylselenonium
S-adenosyl-L-homocysteine zwitterion
Reactome.org link: R-HSA-2408554