Reaction: SeO3(2-) is reduced to H2Se by TXNRD1
- in pathway: Metabolism of ingested H2SeO4 and H2SeO3 into H2Se
Thioredoxin reductase 1 (TXNRD1) homodimer (Sun et al. 1999) is involved in the reduction of selenite (SeO3(2-)) into hydrogen selenide (H2Se). This reaction is inferred from the event in cow (Kumar et al. 1992).
Reaction - small molecule participants:
H2Se [cytosol]
H2O [cytosol]
NADP+ [cytosol]
H+ [cytosol]
SeO3(2-) [cytosol]
NADPH [cytosol]
Reactome.org reaction link: R-HSA-2408558
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Reaction input - small molecules:
hydron
selenite(2-)
NADPH(4-)
Reaction output - small molecules:
selane
water
NADP(3-)
Reactome.org link: R-HSA-2408558