Reaction: atRAL is reduced to atROL
- in pathway: The retinoid cycle in cones (daylight vision)
All-trans-retinal (atRAL) can diffuse across membranes to the cytosol and is reduced to all-trans-retinol (atROL) by the action of a short-chain dehydrogenase/reductase 3 using NADP+/NADPH as cofactor (Haeseleer et al. 1998).
Reaction - small molecule participants:
NADP+ [cytosol]
atROL [cytosol]
H+ [cytosol]
atRAL [cytosol]
NADPH [cytosol]
Reactome.org reaction link: R-HSA-2465940
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Reaction input - small molecules:
hydron
all-trans-retinal
NADPH(4-)
Reaction output - small molecules:
NADP(3-)
all-trans-retinol
Reactome.org link: R-HSA-2465940