Reaction: Exchange of isocitrate and 2-oxoglutarate across the peroxisomal membrane
- in pathway: NADPH regeneration
A specific transport process that exchanges 2-oxoglutarate for isocitrate across a lipid membrane has been reconstituted in vitro with proteins purified from bovine peroxisomal membranes. The specific protein or proteins that mediate this transport process have not yet been identified in any mammalian system, however (Visser et al. 2006).
Reaction - small molecule participants:
2OG [cytosol]
ISCIT [peroxisomal matrix]
ISCIT [cytosol]
2OG [peroxisomal matrix]
Reactome.org reaction link: R-HSA-390347
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Reaction input - small molecules:
D-threo-isocitrate(3-)
2-oxoglutarate(2-)
Reaction output - small molecules:
2-oxoglutarate(2-)
D-threo-isocitrate(3-)
Reactome.org link: R-HSA-390347