Reaction: ITSN1 exchanges GTP for GDP on CDC42, activating it
- in pathway: EPHB-mediated forward signaling
Activated intersectin 1 (ITSN1) activates CDC42 by exchanging GDP with GTP, resulting in high levels of CDC42:GTP in spines.
Reaction - small molecule participants:
GDP [cytosol]
GTP [cytosol]
Reactome.org reaction link: R-HSA-3928632
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Reaction input - small molecules:
GTP(4-)
Reaction output - small molecules:
GDP(3-)
Reactome.org link: R-HSA-3928632