Reaction: sphingosine 1-phosphate => phosphoethanolamine + hexadec-2-enal
- in pathway: Sphingolipid metabolism
SGPL1 (sphingosine-1-phosphate lyase 1), associated with the endoplasmic reticulum membrane, catalyzes the cleavage of cytosolic sphingosine 1-phosphate (S1P) to form phosphoethanolamine (PETA) and hexadec-2-enal (HD2NAL) (Van Veldhoven et al. 2000; Fyrst and Saba 2008).
Reaction - small molecule participants:
HD2NAL [cytosol]
PETA [cytosol]
S1P [cytosol]
Reactome.org reaction link: R-HSA-428676
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Reaction input - small molecules:
sphingosine 1-phosphate(1-)
Reaction output - small molecules:
trans-hexadec-2-enal
O-phosphoethanolamine
Reactome.org link: R-HSA-428676