Molecule: sphingosine 1-phosphate(1-)

The conjugate base of sphingosine 1-phosphate having an anionic phosphate group and a protonated amino group; major species at pH 7.3.
Synonyms for sphingosine 1-phosphate(1-) :
(2S,3R,4E)-2-ammonio-3-hydroxyoctadec-4-en-1-yl phosphate
sphing-4-enine 1-phosphate
sphingosine 1-phosphate anion
Molecular Formula: C18H37NO5P
Molecular wt: 378.46380 g/mole
Charge: -1
SMILES: CCCCCCCCCCCCC\C=C\[C@@H](O)[C@@H]([NH3+])COP([O-])([O-])=O
InChIKey: DUYSYHSSBDVJSM-KRWOKUGFSA-M
InChI=1S/C18H38NO5P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(20)17(19)16-24-25(21,22)23/h14-15,17-18,20H,2-13,16,19H2,1H3,(H2,21,22,23)/p-1/b15-14+/t17-,18+/m0/s1
CHEBI:60119
Sample reactions for this molecule:
S1PR2-5 bind S1P
SPHK1 phosphorylates SPG to S1P
sphingosine 1-phosphate => phosphoethanolamine + hexadec-2-enal
sphingosine 1-phosphate + H2O => sphingosine + orthophosphate [extracellular]
sphingosine 1-phosphate + H2O => sphingosine + orthophosphate [cytosolic - PPAP]
sphingosine 1-phosphate + H2O => sphingosine + orthophosphate [cytosolic - SGPP]
p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate
S1P binds S1PR3 in response to E2 stimulation
SPHK1 phosphorylates sphingosine in response to E2 stimulation
S1PR1 bind S1P