Reaction: Phosphorylation of L1 by EPHB2
- in pathway: L1CAM interactions
EPH kinase Cek5/EPHB2 phosphorylates tyrosine residue in the cytoplasmic domain of NgCAM/L1. The tyrosine 1229 may be the target site. EphrinB/EphB signaling enhances L1-dependent adhesion to substrates including ALCAM and extracellular matrix proteins.
Reaction - small molecule participants:
ADP [cytosol]
ATP [cytosol]
Reactome.org reaction link: R-HSA-443817
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Reaction input - small molecules:
ATP(4-)
Reaction output - small molecules:
ADP(3-)
Reactome.org link: R-HSA-443817