Reaction: PRMT6 methylates arginine-4 of histone H2A (H2AR3)
- in pathway: RMTs methylate histone arginines
PRMT6 is the predominant in vivo methylator of H3R2 (Hyllus et al. 2007, Guccione et al. 2007) and in addition able to methylate arginine-4 of histone H4 (R3H4) and arginine-4 of histone H2A (R3H2A) (Hyllus et al. 2007).
Reaction - small molecule participants:
AdoHcy [nucleoplasm]
AdoMet [nucleoplasm]
Reactome.org reaction link: R-HSA-5205820
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Reaction input - small molecules:
S-adenosyl-L-methionine zwitterion
Reaction output - small molecules:
S-adenosyl-L-homocysteine zwitterion
Reactome.org link: R-HSA-5205820